Cost effectiveness of becaplermin in the treatment of diabetic foot ulcers in four European countries
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چکیده
Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered were uninfected ulcer, infected ulcer, gangrene, healed ulcer, amputation and death. The structure of the model was reported in the paper.
منابع مشابه
Cost effectiveness of Becaplermin in the treatment of diabetic foot ulcers in four European countries.
OBJECTIVE The primary objective of this study was to estimate the cost effectiveness of treating diabetic foot ulcers with becaplermin (Regranex) plus good wound care (GWC) compared with GWC alone in a variety of European healthcare settings. A secondary objective was to analyse the effect of different treatment practices on the economics of caring for diabetic foot ulcers. DESIGN AND SETTING...
متن کاملCost effectiveness of becaplermin in the treatment of diabetic foot ulcers in four European countries
Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered...
متن کاملCost effectiveness of becaplermin in the treatment of diabetic foot ulcers in four European countries
Modelling A Markov model was used to assess the clinical and economic outcomes associated with the two strategies under evaluation in a hypothetical cohort of patients with diabetic foot ulcers. The time horizon of the model was one year and the cycle length was one month. Patients entered the model with uninfected ulcers and, each month, moved across health states. The health states considered...
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Diabetic foot ulcers remain a major cause of morbidity. Significant progress has been accomplished in ulcer healing by improved management of both ischemia and neuropathy in the diabetic foot. Nevertheless, there is a vital need for further improvement. Becaplermin gel represents an important therapeutic advance for diabetic neuropathic foot ulcers with adequate blood supply. Randomized control...
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Diabetic neuropathic foot ulcers represent a serious health care burden to patients and to society. While the management of chronic diabetic foot ulcers has improved in recent years, it remains a frustrating problem for a variety of clinicians. This review examines the scientific underpinnings supporting the use of becaplermin (Regranex((R)); Ortho-McNeil Pharmaceutical, Raritan, NJ), or recomb...
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